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Tb funding hits US$1 bn, but falls short of goals

For the first time in history, funding for tuberculosis (TB) Research and Development (R&D) hit a billion dollars worldwide in 2021.

This marked a significant milestone that nonetheless falls short of what’s needed to stay on track to end TB, this is according to a report released by Treatment Action Group (TAG) and the Stop TB Partnership.

The report, Tuberculosis Research Funding Trends, 2005–2021, highlights that despite reaching US$1 billion in spending, funding for TB R&D is a mere fraction of what’s needed to achieve the United Nations sustainable development goal of ending TB as a pandemic by 2030. According to the report, every day, 4,400 people continue to die from TB, a treatable and curable airborne infectious disease.

National Coordinator of the Kenya Network of TB Champions and Director of Pamoja TB Group Stephen Anguva Shikoli said that TB is an airborne disease meaning that everyone is at risk.

“If we have new innovations, if we have new tools and we have a new vaccine, we will be able to reduce delays in diagnosis and TB deaths around the world,” said Shikoli.

TAG Executive Director Mark Harrington said that they are proud that two decades of activism and scientific advances have led to this unprecedented level of funding for TB research.

“But we remain disappointed at the pandemic inequity that holds back progress on TB diagnosis, prevention, and treatment. This number must grow to US$5 billion per year,” Harrington said.

To meet the 2030 deadline, governments and duty bearers must commit more resources to the fight. The United Nations High-Level Meeting on TB in 2018 set the target of US$2 billion per annum for R&D. After years of chronic underinvestment and devastating disruptions caused by COVID-19, the Stop TB Partnership’s Global Plan to End TB 2023-2030 estimates the funding need for TB R&D to have gone up to US$5 billion per annum.

“I don’t want to celebrate anything. We have reached US$1 billion, but this is far from what is needed to make a serious difference without the US$5 billion annually as outlined in the Global Plan to End TB, 2023–2030,” said Dr. Lucica Ditiu, Executive Director of the Stop TB Partnership. “We should put fundraising efforts in motion and identify smart financing approaches to advance research, develop point-of-care diagnosis, deliver shorter treatments, and get a new TB vaccine by the end of 2025.”

The report reveals that TB R&D funding increases in 2021 were driven mostly by investments in operational and epidemiology research and in diagnostics development. 70 per cent of TB R&D funding came from public entities, with the U.S. National Institutes of Health providing the largest single allocation at US$354 million. However, none of the G7 countries have met their fair share target (defined as 0.1% of overall R&D spending going toward TB research,) with only three countries surveyed—Ireland, the Philippines and South Africa—meeting this benchmark.

Philanthropic spending reached US$140 million worldwide, with 81% coming from the Gates Foundation. Private sector funding lagged at US$102 million, well below its peak of US$145 million a decade ago.

Worth noting, is that a mere 12 per cent of overall spending was on TB vaccines. Without new vaccines against TB, the epidemic will not be stopped. Developing and delivering new TB vaccines in the next decade is within grasp-on the precondition that adequate financing for research is made available without delay.

The billions needed to mount a robust global TB response exceed what’s been invested in TB to date, but they’re little more than a rounding error compared to investments made on SARS-CoV-2 R&D in the past three years.

By Joseph Ng’ang’a

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